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MAF1 Antibody

Product Specifications

Background

This gene encodes a protein that is similar to Maf1, a Saccharomyces cerevisiae protein highly conserved in eukaryotic cells. Yeast Maf1 is a negative effector of RNA polymerase III (Pol III) . It responds to changes in the cellular environment and represses pol III transcription. Biochemical studies identified the initiation factor TFIIIB as a target for Maf1-dependent repression.

NCBI Gene ID

84232

Swiss Prot

Q9H063

Accession Number

Q9H063

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This MAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-117 amino acids from the Central region of human MAF1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

29 kDa

Fragment

Rabbit Ig

Symbol

MAF1

NCBI Official Name

Repressor of RNA polymerase III transcription MAF1 homolog

NCBI Organism

Homo sapiens

Background Reference 01

Kantidakis, T., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (26) :11823-11828 (2010)

Background Reference 02

Shor, B., et al. J. Biol. Chem. 285 (20) :15380-15392 (2010)

Background Reference 03

Johnson, S.S., et al. Mol. Cell 26 (3) :367-379 (2007)

Background Reference 04

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Other Product Names

Repressor of RNA polymerase III transcription MAF1 homolog, MAF1

Tested Applications

WB, IHC-P, Flow

Protein ID

296434582

Physical Properties

Liquid

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