MED25 Antibody
Product Specifications
Background
This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2. [provided by RefSeq].
NCBI Gene ID
81857
Swiss Prot
Q71SY5
Accession Number
Q71SY5
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This MED25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-140 amino acids from the N-terminal region of human MED25.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=55-085
Calculated Molecular Weight
78 kDa
Fragment
Rabbit Ig
Symbol
MED25
NCBI Official Name
Mediator of RNA polymerase II transcription subunit 25
NCBI Organism
Homo sapiens
Background Reference 01
Roupelieva, M., et al. J. Gen. Virol. 91 (PT 5), 1138-1149 (2010) Leal, A., et al. Neurogenetics 10 (4) :275-287 (2009) Lee, H.K., et al. EMBO J. 26 (15) :3545-3557 (2007) Sato, S., et al. Mol. Cell 14 (5) :685-691 (2004) Yang, F., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (8) :2339-2344 (2004)
Other Product Names
Mediator of RNA polymerase II transcription subunit 25, Activator interaction domain-containing protein 1, Activator-recruited cofactor 92 kDa component, ARC92, Mediator complex subunit 25, p78, MED25, ACID1, ARC92, PTOV2
Tested Applications
WB, IHC-P
Protein ID
158706143
Physical Properties
Liquid
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