MED25 Antibody

Product Specifications

Background

This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2. [provided by RefSeq].

NCBI Gene ID

81857

Swiss Prot

Q71SY5

Accession Number

Q71SY5

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This MED25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-140 amino acids from the N-terminal region of human MED25.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

78 kDa

Fragment

Rabbit Ig

Symbol

MED25

NCBI Official Name

Mediator of RNA polymerase II transcription subunit 25

NCBI Organism

Homo sapiens

Background Reference 01

Roupelieva, M., et al. J. Gen. Virol. 91 (PT 5), 1138-1149 (2010) Leal, A., et al. Neurogenetics 10 (4) :275-287 (2009) Lee, H.K., et al. EMBO J. 26 (15) :3545-3557 (2007) Sato, S., et al. Mol. Cell 14 (5) :685-691 (2004) Yang, F., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (8) :2339-2344 (2004)

Other Product Names

Mediator of RNA polymerase II transcription subunit 25, Activator interaction domain-containing protein 1, Activator-recruited cofactor 92 kDa component, ARC92, Mediator complex subunit 25, p78, MED25, ACID1, ARC92, PTOV2