GABRG2 Antibody

Product Specifications

Background

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.

NCBI Gene ID

2566

Swiss Prot

P18507

Accession Number

P18507

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This GABRG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-224 amino acids from the Central region of human GABRG2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat, Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Symbol

GABRG2

NCBI Official Name

Gamma-aminobutyric acid receptor subunit gamma-2

NCBI Organism

Homo sapiens

Background Reference 01

Green, E.K., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (7), 1347-1349 (2010) :

Background Reference 02

Jansen, L.A., et al. Epilepsia 51 (8) :1456-1467 (2010)

Background Reference 03

Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :

Background Reference 04

Shi, X., et al. J. Hum. Genet. 55 (6) :375-378 (2010)

Other Product Names

Gamma-aminobutyric acid receptor subunit gamma-2, GABA (A) receptor subunit gamma-2, GABRG2

Tested Applications

WB, IHC-P

Protein ID

116242488

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

abx938952-01 15 nmol

Human UGGT2 siRNA

Ask

View Details

abx938952-02 30 nmol

Human UGGT2 siRNA

Ask

View Details

abx937723-01 15 nmol

Human TOM1 siRNA

Ask

View Details

abx937723-02 30 nmol

Human TOM1 siRNA

Ask

View Details

bsm-62137R-PerCP-Cy5.5 100 µL

RAP1A/1B Recombinant Antibody, PerCP-Cy5.5 Conjugated

Ask

View Details

MBS2109647-01 0.1 mL

Botin-Linked Monoclonal Antibody to Luteinizing Hormone Beta Polypeptide (LHb)

Ask

View Details