UBA52 Antibody

Product Specifications

Background

Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus, a C-terminal extension protein (CEP) . Multiple processed pseudogenes derived from this gene are present in the genome.

NCBI Gene ID

7311

Swiss Prot

P62987

Accession Number

P62987

Host

Rabbit

Reactivity

Human

Immunogen

This UBA52 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-128 amino acids from the C-terminal region of human UBA52.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Monkey, Mouse, Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

15 kDa

Fragment

Rabbit Ig

Symbol

UBA52

NCBI Official Name

Ubiquitin-60S ribosomal protein L40

NCBI Organism

Homo sapiens

Background Reference 01

Memet, S. Biochem. Pharmacol. 72 (9) :1180-1195 (2006)

Background Reference 02

Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345 (3) :1022-1032 (2006)

Background Reference 03

Foster, L.J., et al. J. Proteome Res. 5 (1) :64-75 (2006)

Background Reference 04

Hu, Y., et al. Mol. Cell Proteomics 4 (12) :2000-2009 (2005)

Other Product Names

Ubiquitin-60S ribosomal protein L40, CEP52, Ubiquitin A-52 residue ribosomal protein fusion product 1, Ubiquitin, 60S ribosomal protein L40, UBA52, UBCEP2