CCL4 Antibody

Product Specifications

Background

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. This protein is similar to CCL4 which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals; most individuals have 1-5 copies in the diploid genome, although rare individuals do not contain this gene at all. The human genome reference assembly contains two copies of this gene. This record represents the more centromeric gene. [provided by RefSeq].

NCBI Gene ID

3883726351

Swiss Prot

P13236

Accession Number

P13236

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This CCL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-48 amino acids from the Central region of human CCL4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

10 kDa

Fragment

Rabbit Ig

Symbol

CCL4

NCBI Official Name

C-C motif chemokine 4

NCBI Organism

Homo sapiens

Background Reference 01

Colobran, R., et al. Clin. Exp. Immunol. 162 (1) :41-52 (2010)

Background Reference 02

Lajoie, J., et al. J. Clin. Immunol. 30 (1) :90-98 (2010)

Background Reference 03

Colobran, R., et al. Genes Immun. 10 (3) :254-259 (2009)

Background Reference 04

Shostakovich-Koretskaya, L., et al. AIDS 23 (6) :679-688 (2009)

Other Product Names

C-C motif chemokine 4, G-26 T-lymphocyte-secreted protein, HC21, Lymphocyte activation gene 1 protein, LAG-1, MIP-1-beta (1-69), Macrophage inflammatory protein 1-beta, MIP-1-beta, PAT 744, Protein H400, SIS-gamma, Small-inducible cytokine A4, T-cell activation protein 2, ACT-2, MIP-1-beta (3-69), CCL4, LAG1, MIP1B, SCYA4