PP1R14C Antibody

Product Specifications

Background

The degree of protein phosphorylation is regulated by a balance of protein kinase and phosphatase activities. Protein phosphatase-1 (PP1; see MIM 176875) is a signal-transducing phosphatase that influences neuronal activity, protein synthesis, metabolism, muscle contraction, and cell division. PPP1R14C is an inhibitor of PP1 (Liu et al., 2002 [PubMed 11812771]) .[supplied by OMIM].

NCBI Gene ID

81706

Swiss Prot

Q8TAE6

Accession Number

Q8TAE6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This PP1R14C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-155 amino acids from the C-terminal region of human PP1R14C.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

18 kDa

Fragment

Rabbit Ig

Symbol

PPP1R14C

NCBI Official Name

Protein phosphatase 1 regulatory subunit 14C

NCBI Organism

Homo sapiens

Background Reference 01

Daskalow, K., et al. Anticancer Res. 30 (5) :1573-1578 (2010)

Background Reference 02

Scholz, S.W., et al. Ann. Neurol. 65 (5) :610-614 (2009)

Background Reference 03

Burgner, D., et al. PLoS Genet. (1), E1000319 (2009) :

Background Reference 04

Mungall, A.J., et al. Nature 425 (6960) :805-811 (2003)

Other Product Names

Protein phosphatase 1 regulatory subunit 14C, Kinase-enhanced PP1 inhibitor, PKC-potentiated PP1 inhibitory protein, Serologically defined breast cancer antigen NY-BR-81, PPP1R14C, KEPI