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TIMP4 Antibody

Product Specifications

Background

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.

NCBI Gene ID

7079

Swiss Prot

Q99727

Accession Number

Q99727

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This TIMP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-74 amino acids from the Central region of human TIMP4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=55-060

Calculated Molecular Weight

26 kDa

Fragment

Rabbit Ig

Symbol

TIMP4

NCBI Official Name

Metalloproteinase inhibitor 4

NCBI Organism

Homo sapiens

Background Reference 01

Nalpas, B., et al. Gut 59 (8) :1120-1126 (2010)

Background Reference 02

Bailey, S.D., et al. Diabetes Care (2010) In press :

Background Reference 03

Wojciechowski, R., et al. Invest. Ophthalmol. Vis. Sci. (2010) In press :

Background Reference 04

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Other Product Names

Metalloproteinase inhibitor 4, Tissue inhibitor of metalloproteinases 4, TIMP-4, TIMP4

Tested Applications

WB, IHC-P

Protein ID

3915135

Physical Properties

Liquid

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