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MUTED Antibody

Product Specifications

Background

This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1) . Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.

NCBI Gene ID

63915

Swiss Prot

Q8TDH9

Accession Number

Q8TDH9

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This MUTED antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the Central region of human MUTED.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Pig

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=55-052

Calculated Molecular Weight

22 kDa

Fragment

Rabbit Ig

Symbol

BLOC1S5

NCBI Official Name

Biogenesis of lysosome-related organelles complex 1 subunit 5

NCBI Organism

Homo sapiens

Background Reference 01

Morris, D.W., et al. Biol. Psychiatry 63 (1) :24-31 (2008)

Background Reference 02

Oh, J.H., et al. Mamm. Genome 16 (12) :942-954 (2005)

Background Reference 03

Starcevic, M., et al. J. Biol. Chem. 279 (27) :28393-28401 (2004)

Background Reference 04

Li, W., et al. Nat. Genet. 35 (1) :84-89 (2003)

Other Product Names

Biogenesis of lysosome-related organelles complex 1 subunit 5, BLOC-1 subunit 5, Protein Muted homolog, BLOC1S5, MUTED

Tested Applications

WB, IHC-P

Protein ID

34582369

Physical Properties

Liquid

Curated Selection

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