MINPP1 Antibody

Product Specifications

Background

This gene encodes multiple inositol polyphosphate phosphatase; an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate; an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.

NCBI Gene ID

9562

Swiss Prot

Q9UNW1

Accession Number

Q9UNW1

Host

Rabbit

Reactivity

Human

Immunogen

This MINPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-55 amino acids from the N-terminal region of human MINPP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

55 kDa

Fragment

Rabbit Ig

Symbol

MINPP1

NCBI Official Name

Multiple inositol polyphosphate phosphatase 1

NCBI Organism

Homo sapiens

Background Reference 01

Newman, A.B., et al. J. Gerontol.Biol. Sci. Med. Sci. 65 (5) :478-487 (2010)

Background Reference 02

Cho, J., et al. Proc. Natl. Acad. Sci. U.S.A. 105 (16) :5998-6003 (2008)

Background Reference 03

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Background Reference 04

Grupe, A., et al. Am. J. Hum. Genet. 78 (1) :78-88 (2006)

Other Product Names

Multiple inositol polyphosphate phosphatase 1,3-bisphosphoglycerate 3-phosphatase,3-BPG phosphatase, Inositol (1,5) -tetrakisphosphate 3-phosphatase, Ins (1,5) P (4) 3-phosphatase, MINPP1, MIPP