A4GALT Antibody

Product Specifications

Background

The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P (k) antigen of the P blood group system. The encoded protein, which is a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor.

NCBI Gene ID

53947

Swiss Prot

Q9NPC4

Accession Number

Q9NPC4

Host

Rabbit

Reactivity

Human

Immunogen

This A4GALT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human A4GALT.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

40 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

A4GALT

NCBI Official Name

Lactosylceramide 4-alpha-galactosyltransferase

NCBI Organism

Homo sapiens

Background Reference 01

Zumbrun, S.D., et al. Infect. Immun. 78 (11) :4488-4499 (2010)

Background Reference 02

Shin, I.S., et al. BMB Rep 42 (5) :310-314 (2009)

Background Reference 03

Lund, N., et al. Blood 113 (20) :4980-4991 (2009)

Background Reference 04

Okuda, T., et al. Glycobiology 18 (12) :1028-1035 (2008)

Other Product Names

Lactosylceramide 4-alpha-galactosyltransferase, Alpha-1,4-N-acetylglucosaminyltransferase, Alpha-1,4-galactosyltransferase, Alpha4Gal-T1, CD77 synthase, Globotriaosylceramide synthase, Gb3 synthase, P1/Pk synthase, UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase, A4GALT, A14GALT, A4GALT1