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HMGB1 Antibody

Product Specifications

Background

Extracellular HMGB1 is an activator of human tumor cell migration operating in concert with EGF. HMGB1 encodes a protein that is potentially involved in the regulation of lipogenic and cholesterogenic gene transcription.

NCBI Gene ID

3146

Swiss Prot

P09429

Accession Number

NP_002119

Host

Rabbit

Reactivity

Bovine, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding to the N terminal region of human HMGB1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cell Cycle, Cancer

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1210 - Hek293 Cell Lysate

Concentration

Batch dependent

Homology

Predicted Homology Based On Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Calculated Molecular Weight

25 kDa

Applications Notes

HMGB1 antibody can be used for detection of HMGB1 by western blot at 0.2 - 1 μ g/mL.

Symbol

HMGB1

NCBI Official Name

High mobility group box 1

NCBI Organism

Homo sapiens

Background Reference 01

Bruneel, A., (2005) Proteomics 5 (15), 3876-3884.

Other Product Names

HMGB1, DKFZp686A04236, HMG1, HMG3, SBP-1

Tested Applications

WB

Protein ID

4504425

Physical Properties

Liquid

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