NUCB1 Antibody
Product Specifications
Background
Calnuc or NUCB1 belongs to the nucleobindin family. It is a major calcium-binding protein of the Golgi and is a good Golgi marker. It may be involved in calcium homeostasis. Calnuc also plays roles in regulation of levels of .-amyloid precursor protein (APP) and its proteolytic metabolites to further affect the patho/physiological functions of APP including Alzheimer's disease pathogenesis. Useful for immunohistochemistry and western blot.
NCBI Gene ID
4924
Swiss Prot
Q02818
Accession Number
NP_006175
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic KLH-conjugated peptide corresponding a region of human NUCB1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Antibody is purified by Protein A/G affinity chromatography method.
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NUCB1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
51 kDa
Applications Notes
NUCB1 antibody can be used for detection of NUCB1 by ELISA at 1:1562500.
Symbol
NUCB1
NCBI Official Name
Nucleobindin 1
NCBI Organism
Homo sapiens
Background Reference 01
Huaxi Xu, et al., (2007) Journal of Neurochemistry 100:1505.
Other Product Names
NUCB1, NUC, CALNUC
Tested Applications
ELISA
Protein ID
20070228
Physical Properties
Liquid
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