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YY1 Antibody

Product Specifications

Background

YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.

NCBI Gene ID

7528

Swiss Prot

P25490

Accession Number

NP_003394

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human YY1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cancer, Signal Transduction, Immunology

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10426 - Fetal Thymus Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store YY1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

45 kDa

Applications Notes

YY1 antibody can be used for detection of YY1 by ELISA at 1:7812500. YY1 antibody can be used for detection of YY1 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

YY1

NCBI Official Name

YY1 transcription factor

NCBI Organism

Homo sapiens

Background Reference 01

Gronroos, E., et al., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12165-12170.

Other Product Names

YY1, DELTA, NF-E1, UCRBP, INO80S, YIN-YANG-1

Tested Applications

ELISA, WB, IHC

Protein ID

4507955

Physical Properties

Liquid

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