GABPB2 Antibody

Product Specifications

Background

GABPB2 is the GA-binding protein transcription factor, beta subunit. It forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. GABPB2 may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

NCBI Gene ID

2553

Swiss Prot

Q06547

Accession Number

NP_005245

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GABPB2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GABPB2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

42 kDa, 41 kDa

Applications Notes

GABPB2 antibody can be used for detection of GABPB2 by ELISA at 1:312500. GABPB2 antibody can be used for detection of GABPB2 by western blot at 2.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

GABPB1

NCBI Official Name

GA binding protein transcription factor, beta subunit 1

NCBI Organism

Homo sapiens

Background Reference 01

Marie, S., et al., (2002) Am. J. Hum. Genet. 71 (1), 14-22.

Other Product Names

GABPB2, HGNC:4074, BABPB2, E4TF1, E4TF1-47, E4TF1-53, E4TF1B, GABPB, GABPB1, NRF2B1, NRF2B2, GABPB2

Tested Applications

ELISA, WB, IHC

Protein ID

8051593

Physical Properties

Liquid

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