RELA Antibody
Product Specifications
Background
P65 is a subunit of the nuclear factor kappa-B, a second messenger, which activates the transcription of a number of genes in multiple tissues. The inhibitory effect of I-kappa-B upon NF-kappa-B in the cytoplasm is exerted primarily through the interaction with p65. p65 shows a weak DNA-binding site which could contribute directly to DNA binding in the NF-kappa-B complex.
NCBI Gene ID
5970
Swiss Prot
Q04206
Accession Number
NP_068810
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RELA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Signal Transduction, Immunology, Apoptosis
Purification
Antibody is purified by Protein A/G affinity chromatography method.
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RELA antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=31-180
Calculated Molecular Weight
60 kDa
Applications Notes
RELA antibody can be used for detection of RELA by ELISA at 1:62500. RELA antibody can be used for detection of RELA by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
RELA
NCBI Official Name
V-rel avian reticuloendotheliosis viral oncogene homolog A
NCBI Organism
Homo sapiens
Background Reference 01
Ruben, S.M., et al., (1991) Science 251 (5000) 1490-1493..
Other Product Names
RELA, p65, NFKB3
Tested Applications
ELISA, WB
Protein ID
223468676
Physical Properties
Liquid
Curated Selection
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