FOS Antibody
Product Specifications
Background
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
NCBI Gene ID
2353
Swiss Prot
P01100
Accession Number
NP_005243
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FOS.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Signal Transduction, Immunology
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store FOS antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
41 kDa
Applications Notes
FOS antibody can be used for detection of FOS by ELISA at 1:312500. FOS antibody can be used for detection of FOS by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
FOS
NCBI Official Name
FBJ murine osteosarcoma viral oncogene homolog
NCBI Organism
Homo sapiens
Background Reference 01
Pan, X., et al., (2005) Biochem. Biophys. Res. Commun. 337 (4), 1052-1058.
Other Product Names
FOS, p55, AP-1, C-FOS
Tested Applications
ELISA, WB
Protein ID
4885241
Physical Properties
Liquid
Frequently Asked Questions
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