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SMAD3 Antibody

Product Specifications

Background

SMAD3 is a member of Smad family proteins. SMAD family is known to be important cytoplasmic mediators of signals from the transforming growth factor-beta (TGF-beta) receptor serine/threonine kinases.

NCBI Gene ID

4088

Swiss Prot

Q92940

Accession Number

NP_005893

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Zebrafish

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMAD3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cancer, Signal Transduction

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. XBL-10409 - Fetal Liver Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SMAD3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

48 kDa

Applications Notes

SMAD3 antibody can be used for detection of SMAD3 by ELISA at 1:62500. SMAD3 antibody can be used for detection of SMAD3 by western blot at 2.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

SMAD3

NCBI Official Name

SMAD family member 3

NCBI Organism

Homo sapiens

Background Reference 01

Cheng, P.L., et al., (2004) Oncogene 23 (47), 7821-7838.

Other Product Names

SMAD3, LDS3, LDS1C, MADH3, JV15-2, HSPC193, HsT17436

Tested Applications

ELISA, WB, IHC

Protein ID

5174513

Physical Properties

Liquid

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