GDI1 Antibody
Product Specifications
Background
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
NCBI Gene ID
2664
Swiss Prot
P31150
Accession Number
NP_001484
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GDI1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GDI1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
51 kDa
Applications Notes
GDI1 antibody can be used for detection of GDI1 by ELISA at 1:312500. GDI1 antibody can be used for detection of GDI1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
GDI1
NCBI Official Name
GDP dissociation inhibitor 1
NCBI Organism
Homo sapiens
Background Reference 01
Papaharalambus, C., et al., (2005) J. Biol. Chem. 280 (19), 18790-18796.
Other Product Names
GDI1, 1A, GDIL, MRX41, MRX48, OPHN2, XAP-4, RABGD1A, RABGDIA
Tested Applications
ELISA, WB
Protein ID
4503971
Physical Properties
Liquid
Curated Selection
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