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GDI1 Antibody

Product Specifications

Background

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.

NCBI Gene ID

2664

Swiss Prot

P31150

Accession Number

NP_001484

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GDI1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GDI1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

51 kDa

Applications Notes

GDI1 antibody can be used for detection of GDI1 by ELISA at 1:312500. GDI1 antibody can be used for detection of GDI1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

GDI1

NCBI Official Name

GDP dissociation inhibitor 1

NCBI Organism

Homo sapiens

Background Reference 01

Papaharalambus, C., et al., (2005) J. Biol. Chem. 280 (19), 18790-18796.

Other Product Names

GDI1, 1A, GDIL, MRX41, MRX48, OPHN2, XAP-4, RABGD1A, RABGDIA

Tested Applications

ELISA, WB

Protein ID

4503971

Physical Properties

Liquid

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