APBA1 Antibody
Product Specifications
Background
APBA1 is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP) . It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. APBA1 is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.
NCBI Gene ID
320
Swiss Prot
Q02410
Accession Number
EAW62487
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human APBA1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1207 - Raji Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store APBA1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=31-125
Calculated Molecular Weight
52 kDa, 93 kDa
Applications Notes
APBA1 antibody can be used for detection of APBA1 by ELISA at 1:62500. APBA1 antibody can be used for detection of APBA1 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
APBA1
NCBI Official Name
Amyloid beta (A4) precursor protein-binding, family A, member 1
NCBI Organism
Homo sapiens
Other Product Names
APBA1, D9S411E, MINT1, X11, X11A, X11ALPHA, LIN10
Tested Applications
ELISA, WB, IHC
Protein ID
119582891
Physical Properties
Liquid
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