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CHRND Antibody

Product Specifications

Background

The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

NCBI Gene ID

1144

Swiss Prot

Q07001

Accession Number

NP_000742

Host

Rabbit

Reactivity

Human, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CHRND.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CHRND antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

59 kDa

Applications Notes

CHRND antibody can be used for detection of CHRND by ELISA at 1:62500. CHRND antibody can be used for detection of CHRND by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

CHRND

NCBI Official Name

Cholinergic receptor, nicotinic, delta (muscle)

NCBI Organism

Homo sapiens

Background Reference 01

Engel, A.G., et al., (1996) Hum. Mol. Genet. 5 (9), 1217-1227.

Other Product Names

CHRND, ACHRD, CMS2A, FCCMS, SCCMS

Tested Applications

ELISA, WB, IHC

Protein ID

4557461

Physical Properties

Liquid

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