RNASEL Antibody
Product Specifications
Background
This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele.
NCBI Gene ID
6041
Swiss Prot
Q05823
Accession Number
NP_066956
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNASEL.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Antibody is purified by Protein A/G affinity chromatography method.
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RNASEL antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=31-079
Calculated Molecular Weight
84 kDa
Applications Notes
RNASEL antibody can be used for detection of RNASEL by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
RNASEL
NCBI Official Name
Ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
NCBI Organism
Homo sapiens
Background Reference 01
Nakazato, H., et al., (2003) Br. J. Cancer 89 (4), 691-696..
Other Product Names
RNASEL, RNS4, PRCA1
Tested Applications
WB
Protein ID
10863929
Physical Properties
Liquid
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