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RNASEL Antibody

Product Specifications

Background

This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele.

NCBI Gene ID

6041

Swiss Prot

Q05823

Accession Number

NP_066956

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RNASEL.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Antibody is purified by Protein A/G affinity chromatography method.

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RNASEL antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

84 kDa

Applications Notes

RNASEL antibody can be used for detection of RNASEL by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

RNASEL

NCBI Official Name

Ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)

NCBI Organism

Homo sapiens

Background Reference 01

Nakazato, H., et al., (2003) Br. J. Cancer 89 (4), 691-696..

Other Product Names

RNASEL, RNS4, PRCA1

Tested Applications

WB

Protein ID

10863929

Physical Properties

Liquid

Curated Selection

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