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RGS10 Antibody

Product Specifications

Background

RGS10 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. It associates specifically with the activated forms of the G protein subunits G (I) -ALPHA and G (Z) - alpha but fails to interact with the structurally and functionally distinct G (S) -alpha subunit. Activity on G (Z) -alpha is inhibited by palmitoylation of the G-protein.

NCBI Gene ID

6001

Swiss Prot

Q96GN0

Accession Number

NP_001005339

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RGS10.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RGS10 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

21 kDa

Applications Notes

RGS10 antibody can be used for detection of RGS10 by ELISA at 1:1562500. RGS10 antibody can be used for detection of RGS10 by western blot at 0.2 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

RGS10

NCBI Official Name

Regulator of G-protein signaling 10

NCBI Organism

Homo sapiens

Background Reference 01

Chatterjee, T.K. et al., (2000) J. Biol. Chem. 275 (31), 24013-24021.

Other Product Names

RGS10

Tested Applications

ELISA, WB

Protein ID

52694755

Physical Properties

Liquid

Frequently Asked Questions

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