RGS10 Antibody
Product Specifications
Background
RGS10 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. It associates specifically with the activated forms of the G protein subunits G (I) -ALPHA and G (Z) - alpha but fails to interact with the structurally and functionally distinct G (S) -alpha subunit. Activity on G (Z) -alpha is inhibited by palmitoylation of the G-protein.
NCBI Gene ID
6001
Swiss Prot
Q96GN0
Accession Number
NP_001005339
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RGS10.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RGS10 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=31-068
Calculated Molecular Weight
21 kDa
Applications Notes
RGS10 antibody can be used for detection of RGS10 by ELISA at 1:1562500. RGS10 antibody can be used for detection of RGS10 by western blot at 0.2 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
RGS10
NCBI Official Name
Regulator of G-protein signaling 10
NCBI Organism
Homo sapiens
Background Reference 01
Chatterjee, T.K. et al., (2000) J. Biol. Chem. 275 (31), 24013-24021.
Other Product Names
RGS10
Tested Applications
ELISA, WB
Protein ID
52694755
Physical Properties
Liquid
Curated Selection
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