RGS3 Antibody

RGS3 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic, but G-protein activation leads to translocation of this protein to the plasma membrane. A nuclear form of this protein has also been described, but its sequence has not been identified. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature of some transcripts is not yet known.

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RGS3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

RGS3 antibody can be used for detection of RGS3 by ELISA at 1:62500. RGS3 antibody can be used for detection of RGS3 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.