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YWHAH Antibody

Product Specifications

Background

The YWHAH gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

NCBI Gene ID

7533

Swiss Prot

Q04917

Accession Number

NP_003396

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human YWHAH.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cell Cycle, Cancer, Signal Transduction, Neuroscience

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1304 - Human Liver Tissue Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store YWHAH antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

28 kDa

Applications Notes

YWHAH antibody can be used for detection of YWHAH by ELISA at 1:1562500. YWHAH antibody can be used for detection of YWHAH by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

YWHAH

NCBI Official Name

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta

NCBI Organism

Homo sapiens

Background Reference 01

Kilani, R.T., (2007) J. Rheumatol. 34 (8), 1650-1657.

Other Product Names

YWHAH, YWHA1

Tested Applications

ELISA, WB

Protein ID

4507951

Physical Properties

Liquid

Frequently Asked Questions

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