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TP53 Antibody

Product Specifications

Background

TP53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.

NCBI Gene ID

7157

Swiss Prot

P04637

Accession Number

NP_000537

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TP53.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cell Cycle, Cancer, Apoptosis

Purification

Antibody is purified by Protein A/G affinity chromatography method.

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TP53 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

44 kDa

Applications Notes

TP53 antibody can be used for detection of TP53 by ELISA at 1:62500. TP53 antibody can be used for detection of TP53 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

TP53

NCBI Official Name

Tumor protein p53

NCBI Organism

Homo sapiens

Background Reference 01

Zakut-Houri, R., et al., (1985) EMBO J. 4: 1251-1255..

Other Product Names

TP53, P53, BCC7, LFS1, TRP53

Tested Applications

ELISA, WB

Protein ID

120407068

Physical Properties

Liquid

Frequently Asked Questions

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