TP53 Antibody
Product Specifications
Background
TP53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.
NCBI Gene ID
7157
Swiss Prot
P04637
Accession Number
NP_000537
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TP53.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cell Cycle, Cancer, Apoptosis
Purification
Antibody is purified by Protein A/G affinity chromatography method.
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TP53 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=31-024
Calculated Molecular Weight
44 kDa
Applications Notes
TP53 antibody can be used for detection of TP53 by ELISA at 1:62500. TP53 antibody can be used for detection of TP53 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TP53
NCBI Official Name
Tumor protein p53
NCBI Organism
Homo sapiens
Background Reference 01
Zakut-Houri, R., et al., (1985) EMBO J. 4: 1251-1255..
Other Product Names
TP53, P53, BCC7, LFS1, TRP53
Tested Applications
ELISA, WB
Protein ID
120407068
Physical Properties
Liquid
Curated Selection
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