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TNFRSF18 Antibody

Product Specifications

Background

The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+) CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.

NCBI Gene ID

8784

Swiss Prot

Q9Y5U5

Accession Number

NP_004186

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TNFRSF18.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Cancer, Signal Transduction, Apoptosis

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TNFRSF18 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=31-021

Calculated Molecular Weight

26 kDa

Applications Notes

TNFRSF18 antibody can be used for detection of TNFRSF18 by ELISA at 1:312500. TNFRSF18 antibody can be used for detection of TNFRSF18 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

TNFRSF18

NCBI Official Name

Tumor necrosis factor receptor superfamily, member 18

NCBI Organism

Homo sapiens

Background Reference 01

Clark, H.F., et al., (2003) Genome Res. 13 (10), 2265-2270.

Other Product Names

TNFRSF18, AITR, GITR, CD357, GITR-D

Tested Applications

ELISA, WB, IHC

Protein ID

4759246

Physical Properties

Liquid

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