TNFRSF18 Antibody
Product Specifications
Background
The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+) CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.
NCBI Gene ID
8784
Swiss Prot
Q9Y5U5
Accession Number
NP_004186
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TNFRSF18.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer, Signal Transduction, Apoptosis
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TNFRSF18 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
26 kDa
Applications Notes
TNFRSF18 antibody can be used for detection of TNFRSF18 by ELISA at 1:312500. TNFRSF18 antibody can be used for detection of TNFRSF18 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TNFRSF18
NCBI Official Name
Tumor necrosis factor receptor superfamily, member 18
NCBI Organism
Homo sapiens
Background Reference 01
Clark, H.F., et al., (2003) Genome Res. 13 (10), 2265-2270.
Other Product Names
TNFRSF18, AITR, GITR, CD357, GITR-D
Tested Applications
ELISA, WB, IHC
Protein ID
4759246
Physical Properties
Liquid
Frequently Asked Questions
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