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RIPK1 Antibody

Product Specifications

Background

FAK overexpression in human tumors provides a survival signal function by binding to RIP and inhibiting its interaction with the death receptor complex.

NCBI Gene ID

8737

Swiss Prot

Q13546

Accession Number

NP_003795

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RIPK1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction, Immunology, Apoptosis

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1205 - Jurkat Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RIPK1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

76 kDa

Applications Notes

RIPK1 antibody can be used for detection of RIPK1 by ELISA at 1:312500. RIPK1 antibody can be used for detection of RIPK1 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

RIPK1

NCBI Official Name

Receptor (TNFRSF) -interacting serine-threonine kinase 1

NCBI Organism

Homo sapiens

Background Reference 01

Kurenova, E., et al., (2004) Mol. Cell. Biol. 24 (10), 4361-4371.

Other Product Names

RIPK1, RIP, RIP1

Tested Applications

ELISA, WB

Protein ID

57242761

Physical Properties

Liquid

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