DIABLO Antibody
Product Specifications
Background
DIABLO is an inhibitor of apoptosis protein (IAP) -binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Several alternatively spliced transcript variants that encode distinct isoforms have been described for this gene but the validity of some transcripts, and their predicted ORFs, has not been determined conclusively.
NCBI Gene ID
56616
Swiss Prot
Q502X2
Accession Number
NP_620308
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DIABLO.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store DIABLO antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=31-015
Calculated Molecular Weight
21 kDa, 27 kDa, 22 kDa
Applications Notes
DIABLO antibody can be used for detection of DIABLO by ELISA at 1:312500. DIABLO antibody can be used for detection of DIABLO by western blot at 0.3125 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
DIABLO
NCBI Official Name
Diablo, IAP-binding mitochondrial protein
NCBI Organism
Homo sapiens
Background Reference 01
Samuel, T., et al., (2006) J. Biol. Chem. 281 (2), 1080-1090.
Other Product Names
DIABLO, SMAC, DFNA64
Tested Applications
ELISA, WB
Protein ID
21070978
Physical Properties
Liquid
Curated Selection
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