BCL2L1 Antibody
Product Specifications
Background
BCL2L1 encodes a protein which belongs to the BCL-2 protein family. The proteins encoded by BCL2L1 are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.
NCBI Gene ID
598
Swiss Prot
Q07817
Accession Number
NP_612815
Host
Rabbit
Reactivity
Human, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BCL2L1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10426 - Fetal Thymus Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store BCL2L1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
26 kDa, 19 kDa
Applications Notes
BCL2L1 antibody can be used for detection of BCL2L1 by ELISA at 1:62500. BCL2L1 antibody can be used for detection of BCL2L1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
BCL2L1
NCBI Official Name
BCL2-like 1
NCBI Organism
Homo sapiens
Background Reference 01
Bachelor, M.A. et al., (2004) J. Biol. Chem. 279 (41), 42658-42668.
Other Product Names
BCL2L1, BCLX, BCL2L, BCLXL, BCLXS, Bcl-X, bcl-xL, bcl-xS, PPP1R52, BCL-XL/S
Tested Applications
ELISA, WB
Protein ID
20336335
Physical Properties
Liquid
Frequently Asked Questions
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