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SERPINA1 Antibody

Product Specifications

Background

Alpha-1-antitrypsin is a protease inhibitor, deficiency of which is associated with emphysema and liver disease. The protein is encoded by a gene (PI) located on the distal long arm of chromosome 14.

NCBI Gene ID

5265

Swiss Prot

P01009

Accession Number

NP_000286

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SERPINA1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction, Immunology

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SERPINA1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

46 kDa

Applications Notes

SERPINA1 antibody can be used for detection of SERPINA1 by ELISA at 1:12500. SERPINA1 antibody can be used for detection of SERPINA1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

SERPINA1

NCBI Official Name

Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

NCBI Organism

Homo sapiens

Background Reference 01

Knappstein, S., et al., (2004) Infect. Immun. 72 (8), 4344-4350.

Other Product Names

SERPINA1, PI, A1A, AAT, PI1, A1AT, PRO2275, alpha1AT

Tested Applications

ELISA, WB, IHC

Protein ID

50363217

Physical Properties

Liquid

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