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FEM1B Antibody

Product Specifications

Background

FEM1B is a component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. It involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. FEM1B also involved in glucose homeostasis in pancreatic islet.

NCBI Gene ID

10116

Swiss Prot

Q9UK73

Accession Number

NP_056137

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FEM1B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction, Apoptosis

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

721_B Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store FEM1B antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

69 kDa

Applications Notes

FEM1B antibody can be used for detection of FEM1B by ELISA at 1:1562500. FEM1B antibody can be used for detection of FEM1B by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

FEM1B

NCBI Official Name

Fem-1 homolog b (C. elegans)

NCBI Organism

Homo sapiens

Background Reference 01

Kamura, T., (2004) Genes Dev. 18 (24), 3055-3065.

Other Product Names

FEM1B, DKFZp451E0710, FIAA, F1AA, F1A-ALPHA, FEM1-beta

Tested Applications

ELISA, WB

Protein ID

7657265

Physical Properties

Liquid

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