TNP1 Antibody
Product Specifications
Background
TNP1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines.Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 [PubMed 2249851]) .
NCBI Gene ID
7141
Swiss Prot
P09430
Accession Number
NP_003275
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TNP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
721_B Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TNP1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
6 kDa
Applications Notes
TNP1 antibody can be used for detection of TNP1 by ELISA at 1:62500. TNP1 antibody can be used for detection of TNP1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TNP1
NCBI Official Name
Transition protein 1 (during histone to protamine replacement)
NCBI Organism
Homo sapiens
Background Reference 01
Jedrzejczak, P., (2007) Arch. Androl. 53 (4), 199-205.
Other Product Names
TNP1, TP1
Tested Applications
ELISA, WB
Protein ID
4507629
Physical Properties
Liquid
Curated Selection
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