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TNP1 Antibody

Product Specifications

Background

TNP1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines.Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 [PubMed 2249851]) .

NCBI Gene ID

7141

Swiss Prot

P09430

Accession Number

NP_003275

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TNP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

721_B Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TNP1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

6 kDa

Applications Notes

TNP1 antibody can be used for detection of TNP1 by ELISA at 1:62500. TNP1 antibody can be used for detection of TNP1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

TNP1

NCBI Official Name

Transition protein 1 (during histone to protamine replacement)

NCBI Organism

Homo sapiens

Background Reference 01

Jedrzejczak, P., (2007) Arch. Androl. 53 (4), 199-205.

Other Product Names

TNP1, TP1

Tested Applications

ELISA, WB

Protein ID

4507629

Physical Properties

Liquid

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