CCDC50 Antibody
Product Specifications
Background
CCDC50 is a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF) -mediated cell signaling.
NCBI Gene ID
152137
Swiss Prot
Q8IVM0
Accession Number
NP_848018
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCDC50.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
721_B Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CCDC50 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
56 kDa
Applications Notes
CCDC50 antibody can be used for detection of CCDC50 by ELISA at 1:1562500. CCDC50 antibody can be used for detection of CCDC50 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CCDC50
NCBI Official Name
Coiled-coil domain containing 50
NCBI Organism
Homo sapiens
Background Reference 01
Bohgaki, M., (2008) Biochim. Biophys. Acta 1783 (5), 826-837.
Other Product Names
CCDC50, C3orf6, DFNA44, YMER
Tested Applications
ELISA, WB
Protein ID
41281911
Physical Properties
Liquid
Curated Selection
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