ZCCHC12 Antibody
Product Specifications
Background
ZCCHC12 contains 1 CCHC-type zinc finger. ZCCHC12 is the transcriptional coactivator in the bone morphogenetic protein (BMP) -signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression.
NCBI Gene ID
170261
Swiss Prot
Q6PEW1
Accession Number
NP_776159
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZCCHC12.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ZCCHC12 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
45 kDa
Applications Notes
ZCCHC12 antibody can be used for detection of ZCCHC12 by ELISA at 1:1562500. ZCCHC12 antibody can be used for detection of ZCCHC12 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ZCCHC12
NCBI Official Name
Zinc finger, CCHC domain containing 12
NCBI Organism
Homo sapiens
Background Reference 01
Cho, G., (2008) Mol. Cell. Biol. 28 (5), 1565-1572.
Other Product Names
ZCCHC12, FLJ16123, SIZN, SIZN1, PNMA7A
Tested Applications
ELISA, WB
Protein ID
28557790
Physical Properties
Liquid
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