ASB11 Antibody
Product Specifications
Background
ASB11 is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation.The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Two transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
140456
Swiss Prot
Q8WXH4
Accession Number
NP_001012428
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ASB11.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ASB11 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
33 kDa
Applications Notes
ASB11 antibody can be used for detection of ASB11 by ELISA at 1:62500. ASB11 antibody can be used for detection of ASB11 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ASB11
NCBI Official Name
Ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase
NCBI Organism
Homo sapiens
Background Reference 01
Diks, S.H., (2006) J. Cell Biol. 174 (4), 581-592.
Other Product Names
ASB11, DKFZp779E2460, MGC119168, MGC119169
Tested Applications
ELISA, WB
Protein ID
60218887
Physical Properties
Liquid
Curated Selection
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