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TRIP6 Antibody

Product Specifications

Background

TRIP6 is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of TRIP6 to the plasma membrane occurs in a lysophosphatidic acid (LPA) -dependent manner and it regulates LPA-induced cell migration.This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA) -dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

NCBI Gene ID

7205

Swiss Prot

Q15654

Accession Number

NP_003293

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRIP6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Transcription, Cancer, Signal Transduction

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TRIP6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

50 kDa

Applications Notes

TRIP6 antibody can be used for detection of TRIP6 by ELISA at 1:1562500. TRIP6 antibody can be used for detection of TRIP6 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

TRIP6

NCBI Official Name

Thyroid hormone receptor interactor 6

NCBI Organism

Homo sapiens

Background Reference 01

Bai, C.Y., J. Cell. Sci. 120 (PT 16), 2828-2837 (2007) .

Other Product Names

TRIP6, MGC10556, MGC10558, MGC29959, MGC3837, MGC4423, OIP1, ZRP-1, OIP-1, TRIP-6, TRIP6i2

Tested Applications

ELISA, WB

Protein ID

91208423

Physical Properties

Liquid

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