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ORAI1 Antibody

Product Specifications

Background

ORAI1 belongs to the Orai family. ORAI1 (CRACM1) is a plasma membrane protein essential for store-operated calcium entry. Defects in ORAI1 are a cause of severe combined immunodeficiency with CRAC channel dysfunction (CRAC-SCID) .CRACM1 is a plasma membrane protein essential for store-operated calcium entry (Vig et al., 2006 [PubMed 16645049]) .

NCBI Gene ID

84876

Swiss Prot

Q96D31

Accession Number

NP_116179

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ORAI1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Membrane, Cancer

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ORAI1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

33 kDa

Applications Notes

ORAI1 antibody can be used for detection of ORAI1 by ELISA at 1:1562500. ORAI1 antibody can be used for detection of ORAI1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

ORAI1

NCBI Official Name

ORAI calcium release-activated calcium modulator 1

NCBI Organism

Homo sapiens

Background Reference 01

Peel, S.E., (2008) Am. J. Respir. Cell Mol. Biol. 38 (6), 744-749.

Other Product Names

ORAI1, CRACM1, FLJ14466, TMEM142A, IMD9, ORAT1

Tested Applications

ELISA, WB

Protein ID

38016943

Physical Properties

Liquid

Frequently Asked Questions

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