ORAI1 Antibody
Product Specifications
Background
ORAI1 belongs to the Orai family. ORAI1 (CRACM1) is a plasma membrane protein essential for store-operated calcium entry. Defects in ORAI1 are a cause of severe combined immunodeficiency with CRAC channel dysfunction (CRAC-SCID) .CRACM1 is a plasma membrane protein essential for store-operated calcium entry (Vig et al., 2006 [PubMed 16645049]) .
NCBI Gene ID
84876
Swiss Prot
Q96D31
Accession Number
NP_116179
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ORAI1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ORAI1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=30-572
Calculated Molecular Weight
33 kDa
Applications Notes
ORAI1 antibody can be used for detection of ORAI1 by ELISA at 1:1562500. ORAI1 antibody can be used for detection of ORAI1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
ORAI1
NCBI Official Name
ORAI calcium release-activated calcium modulator 1
NCBI Organism
Homo sapiens
Background Reference 01
Peel, S.E., (2008) Am. J. Respir. Cell Mol. Biol. 38 (6), 744-749.
Other Product Names
ORAI1, CRACM1, FLJ14466, TMEM142A, IMD9, ORAT1
Tested Applications
ELISA, WB
Protein ID
38016943
Physical Properties
Liquid
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