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TTC5 Antibody

Product Specifications

Background

TTC5 is an adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. It is required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. It prevents p53/TP53 degradation by MDM2.

NCBI Gene ID

91875

Swiss Prot

Q8N0Z6

Accession Number

NP_612385

Host

Rabbit

Reactivity

Human

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TTC5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1211 - HepG2 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TTC5 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

49 kDa

Applications Notes

TTC5 antibody can be used for detection of TTC5 by ELISA at 1:312500. TTC5 antibody can be used for detection of TTC5 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

TTC5

NCBI Official Name

Tetratricopeptide repeat domain 5

NCBI Organism

Homo sapiens

Background Reference 01

Demonacos, C., (2001) Mol. Cell 8 (1), 71-84.

Other Product Names

TTC5, Strap

Tested Applications

ELISA, WB

Protein ID

226498382

Physical Properties

Liquid

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