CHST14 Antibody
Product Specifications
Background
CHST14 belongs to the sulfotransferase 2 family. CHST14 catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. It transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. It transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. CHST14 has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA.
NCBI Gene ID
113189
Swiss Prot
Q8NCH0
Accession Number
AAH23653
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CHST14.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CHST14 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=30-488
Calculated Molecular Weight
35 kDa
Applications Notes
CHST14 antibody can be used for detection of CHST14 by ELISA at 1:312500. CHST14 antibody can be used for detection of CHST14 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
CHST14
NCBI Official Name
Carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
NCBI Organism
Homo sapiens
Other Product Names
CHST14, D4ST-1, D4ST1, HD4ST, HNK1ST, ATCS, EDSMC1
Tested Applications
ELISA, WB
Protein ID
40289703
Physical Properties
Liquid
Curated Selection
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