FDFT1 Antibody
Product Specifications
Background
FDFT1 is a membrane-associated enzyme located at a branch point in the mevalonate pathway. The protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
2222
Swiss Prot
P37268
Accession Number
NP_004453
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FDFT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store FDFT1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=30-428
Calculated Molecular Weight
48 kDa
Applications Notes
FDFT1 antibody can be used for detection of FDFT1 by ELISA at 1:12500. FDFT1 antibody can be used for detection of FDFT1 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
FDFT1
NCBI Official Name
Farnesyl-diphosphate farnesyltransferase 1
NCBI Organism
Homo sapiens
Background Reference 01
Do, R., (er) Hum. Mutat. (2008) In press.
Other Product Names
FDFT1, DGPT, ERG9, SQS, SS
Tested Applications
ELISA, WB
Protein ID
67089147
Physical Properties
Liquid
Curated Selection
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