FNTA Antibody
Product Specifications
Background
Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. FNTA is the alpha subunit of these transferases.Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants encoding different isoforms.
NCBI Gene ID
2339
Swiss Prot
A6NJW0
Accession Number
NP_001018197
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FNTA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store FNTA antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
36 kDa
Applications Notes
FNTA antibody can be used for detection of FNTA by ELISA at 1:62500. FNTA antibody can be used for detection of FNTA by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
FNTA
NCBI Official Name
Farnesyltransferase, CAAX box, alpha
NCBI Organism
Homo sapiens
Background Reference 01
Veluthakal, R., (2007) Diabetes 56 (1), 204-210.
Other Product Names
FNTA, FPTA, MGC99680, PGGT1A, PTAR2
Tested Applications
ELISA, WB
Protein ID
66882532
Physical Properties
Liquid
Curated Selection
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