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DSTN Antibody

Product Specifications

Background

DSTN belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. It is the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin) .The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin) . Two transcript variants encoding distinct isoforms have been identified for this gene.

NCBI Gene ID

11034

Swiss Prot

P60981

Accession Number

NP_006861

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DSTN.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Antibody is purified by peptide affinity chromatography method.

Positive Control

Cat. No. 1219 - MCF7 Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store DSTN antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Calculated Molecular Weight

18 kDa

Applications Notes

DSTN antibody can be used for detection of DSTN by ELISA at 1:62500. DSTN antibody can be used for detection of DSTN by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

DSTN

NCBI Official Name

Destrin (actin depolymerizing factor)

NCBI Organism

Homo sapiens

Background Reference 01

Estornes, Y., (2007) Int. J. Cancer 121 (10), 2162-2171.

Other Product Names

DSTN, ACTDP, ADF, bA462D18.2, HEL32

Tested Applications

ELISA, WB

Protein ID

5802966

Physical Properties

Liquid

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