RARRES3 Antibody
Product Specifications
Background
Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES3 is thought act as a tumor suppressor or growth regulator.Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator.
NCBI Gene ID
5920
Swiss Prot
Q9UL19
Accession Number
NP_004576
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RARRES3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RARRES3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=30-204
Calculated Molecular Weight
18 kDa
Applications Notes
RARRES3 antibody can be used for detection of RARRES3 by ELISA at 1:312500. RARRES3 antibody can be used for detection of RARRES3 by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
RARRES3
NCBI Official Name
Retinoic acid receptor responder (tazarotene induced) 3
NCBI Organism
Homo sapiens
Background Reference 01
Lotz, K., (2005) Int. J. Cancer 116 (6), 894-902.
Other Product Names
RARRES3, HRASLS4, MGC8906, RIG1, TIG3, HRSL4, PLA1/2-3
Tested Applications
ELISA, WB, IHC
Protein ID
149588791
Physical Properties
Liquid
Curated Selection
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