TMPRSS11D Antibody
Product Specifications
Background
TMPRSS11D is a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.
NCBI Gene ID
9407
Swiss Prot
O60235
Accession Number
NP_004253
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TMPRSS11D.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Signal Transduction
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TMPRSS11D antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
46 kDa
Applications Notes
TMPRSS11D antibody can be used for detection of TMPRSS11D by ELISA at 1:62500. TMPRSS11D antibody can be used for detection of TMPRSS11D by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TMPRSS11D
NCBI Official Name
Transmembrane protease, serine 11D
NCBI Organism
Homo sapiens
Background Reference 01
Matsushima, R., Am. J. Physiol. Lung Cell Mol. Physiol. 290 (2), L385-L395 (2006) .
Other Product Names
TMPRSS11D, HAT, MGC150587, MGC150588
Tested Applications
ELISA, WB, IHC
Protein ID
4758508
Physical Properties
Liquid
Frequently Asked Questions
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