SWAP70 Antibody
Product Specifications
Background
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. SWAP70 also mediates signaling of membrane ruffling. It regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4) -bisphosphate production and cell protrusion.
NCBI Gene ID
23075
Swiss Prot
Q9UH65
Accession Number
NP_055870
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SWAP70.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SWAP70 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=30-175
Calculated Molecular Weight
69 kDa
Applications Notes
SWAP70 antibody can be used for detection of SWAP70 by ELISA at 1:62500. SWAP70 antibody can be used for detection of SWAP70 by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SWAP70
NCBI Official Name
SWAP switching B-cell complex 70kDa subunit
NCBI Organism
Homo sapiens
Background Reference 01
Liu, J., (2007) J. Histochem. Cytochem. 55 (7), 701-708.
Other Product Names
SWAP70, FLJ39540, HSPC321, KIAA0640, SWAP-70
Tested Applications
ELISA, WB
Protein ID
93102364
Physical Properties
Liquid
Curated Selection
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