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PPIF Antibody

Product Specifications

Background

PPIF is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.

NCBI Gene ID

10105

Swiss Prot

P30405

Accession Number

NP_005720

Host

Rabbit

Reactivity

Human, Rat, Dog

Immunogen

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PPIF.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

Antibody is purified by protein A chromatography method.

Positive Control

Tranfected 293T Cell Lysate

Concentration

Batch dependent

Buffer

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PPIF antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=30-165

Calculated Molecular Weight

19 kDa

Applications Notes

PPIF antibody can be used for detection of PPIF by ELISA at 1:62500. PPIF antibody can be used for detection of PPIF by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Symbol

PPIF

NCBI Official Name

Peptidylprolyl isomerase F

NCBI Organism

Homo sapiens

Background Reference 01

Clark, H.F., (2003) Genome Res. 13 (10), 2265-2270.

Other Product Names

PPIF, CYP3, Cyp-D, FLJ90798, MGC117207, CypD, CyP-M

Tested Applications

ELISA, WB

Protein ID

5031987

Physical Properties

Liquid

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