NR3C2 Antibody
Product Specifications
Background
NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
NCBI Gene ID
4306
Swiss Prot
P08235
Accession Number
NP_000892
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR3C2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Signal Transduction
Purification
Antibody is purified by protein A chromatography method.
Positive Control
A172 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NR3C2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
107 kDa
Applications Notes
NR3C2 antibody can be used for detection of NR3C2 by ELISA at 1:312500. NR3C2 antibody can be used for detection of NR3C2 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
NR3C2
NCBI Official Name
Nuclear receptor subfamily 3, group C, member 2
NCBI Organism
Homo sapiens
Background Reference 01
Liu, G., (2006) Biochem. Biophys. Res. Commun. 342 (4), 1291-1296.
Other Product Names
NR3C2, MCR, MGC133092, MLR, MR, NR3C2VIT
Tested Applications
ELISA, WB, IHC
Protein ID
158508572
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15263970 1 Vial
Lentiviral mouse Prpf4 shRNA (UAS) - Lentiviral mouse Prpf4 shRNA (UAS) (100)
Ask
View Details