SMPD2 Antibody
Product Specifications
Background
SMPD2 converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor) . The physiological substrate seems to be Lyso-PAF.
NCBI Gene ID
6610
Swiss Prot
O60906
Accession Number
NP_003071
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMPD2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SMPD2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
48 kDa
Applications Notes
SMPD2 antibody can be used for detection of SMPD2 by ELISA at 1:1562500. SMPD2 antibody can be used for detection of SMPD2 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SMPD2
NCBI Official Name
Sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
NCBI Organism
Homo sapiens
Background Reference 01
Kimura, K., (2006) Genome Res. 16 (1), 55-65.
Other Product Names
SMPD2, NSMASE, ISC1, NSMASE1
Tested Applications
ELISA, WB
Protein ID
92859618
Physical Properties
Liquid
Curated Selection
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